The biggest problem many people have with Metformin is that it causes such misery when it hits their stomachs that they can't keep taking it even though they know it is the safest and most effective of all the oral diabetes drugs.In many cases all that is needed is some patience. After a rocky first few days many people's bodies calm down and metformin becomes quite tolerable.If you are taking the regular form of Metformin with meals and still having serious stomach issues after a week of taking
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